Publication Date    Citation and Links

Brooks-Worrell BM, Tjaden AH, Edelstein SL, Palomino B, Utzschneider KM, Arslanian S, Mather KJ, Buchanan TA, Nadeau KJ, Atkinson K, Barengolts E, Kahn SE, Palmer JP, RISE Consortium. Islet Autoimmunity in Adults With Impaired Glucose Tolerance and Recently Diagnosed, Treatment Naïve Type 2 Diabetes in the Restoring Insulin SEcretion (RISE) Study. Diabetes Care. Front. Immunol., 26 April 2021 |


Mather KJ, Tjaden AH, Hoehn A, Nadeau KJ, Buchanan TA, Kahn SE, Arslanian SA, Caprio S, Atkinson KM, Cree-Green M, Utzschneider KM, Edelstein SL. Precision and accuracy of hyperglycemic clamps in a multicenter study. Am J Physiol Endocrinol Metab. 2021 Apr 1;320(4):E797-E807. doi: 10.1152/ajpendo.00598.2020. Epub 2021 Mar 1. PMID: 33645253. Pubmed Journal * Full Text


Mokhlesi B, Tjaden AH, Temple KA, Edelstein SL, Sam S,  Nadeau KJ, Hannon TS, Manchanda S, Mather KJ, Kahn SE, Ehrmann DA, Van Cauter E, for the RISE Consortium. Obstructive Sleep Apnea, Glucose Tolerance, and β-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2021 Apr;44(4):993-1001. doi: 10.2337/dc20-2127. Epub 2021 Feb 5. PMID: 33547205; PMCID: PMC7985427. Pubmed Journal

Arslanian SA, El Ghormli L, Kim JY, Tjaden AH, Barengolts E, Caprio S, Hannon TS, Mather KJ, Nadeau KJ, Utzschneider KM, Kahn SE for the RISE Consortium. OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function. Diabetes Care 2021 Jan; dc202134. Pubmed Journal 

Utzschneider KM, Tripputi MT, Kozedub A, Mather KJ, Nadeau KJ, Edelstein SL, Hannon TS, Arslanian SA, Cree-Green M, Buchanan TA, Caprio S, Maria A, The RISE Consortium.  β-cells in youth witih impaired glucose tolerance or early type 2 diabetes secrete more insulin and are more responsive than in adults. 2020 Dec;21(8):1421-1429. doi:  10.1111/pedi.13113. PMID: 32902875. PMCID: PMC7642023.  Pubmed * Journal 


Hannon TS, Edelstein SL, Arslanian SA, Caprio S, Zeitler PS, Buchanan TA, Ehrmann DA, Mather KJ, Tripputi M, Kahn SE, Nadeau KJ, The RISE Consortium. Withdrawal of medications leads to worsening of OGTT parameters in youth with impaired glucose tolerance or recently-diagnosed type 2 diabetes. Pediatr Diabetes. 2020 Dec;21(8):1437-1446. doi: 10.1111/pedi.13129. Epub 2020 Oct 13. PMID: 32985775; PMCID: PMC7642167. Pubmed * Journal 

09/04/2019   Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Nadeau KJ, Hannon TS, Manchanda S, Sam S, Barengolts E, Utzschneider KM, Ehrmann DA, Van Cauter E; RISE Consortium. The association of sleep disturbances with glycemia and obesity in youth at risk for or with recently diagnosed type 2 diabetes. Pediatr Diabetes. 2019 Dec;20(8):1056-1063. doi: 10.1111/pedi.12917. PMID: 31486162; PMCID: PMC7199716. Pubmed Journal 

The RISE Consortium. Obesity and insulin sensitivity effects on cardiovascular risk factors: Comparisons of obese dysglycemic youth and adults. Pediatric Diabetes. 2019 Nov;20(7):849-860. doi: 10.1111/pedi.12883. 
PMID: 31301210. PMCID: PMC6786916. PubMed Journal 


The RISE Consortium. Effects of Treatment of Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes With Metformin Alone or in Combination With Insulin Glargine on β-Cell Function: Comparison of Responses In Youth And Adults. Diabetes 2019 Aug;68(8):1670-1680; db190299. PMID: 31178433. PMCID: PMC6692818. PubMed * Journal 

06/09/2019   The RISE Consortium. Lack of Durable Improvements in β-Cell Function Following Withdrawal of Pharmacological Interventions in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes. Diabetes Care 2019 Sep;42(9):1742-1751. dc190556; DOI: 10.2337/dc19-0556. PMID: 31178434.  PMCID: PMC6702605PubMed * Journal 
06/09/2019   Temple KA, Tjaden AH, Atkinson KM, Barengolts E, Hannon TS, Mather KJ, Utzschneider KM, Edelstein SL, Ehrmann DA, Mokhlesi B. Association of Habitual Daily Physical Activity With Glucose Tolerance and β-Cell Function in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes From the Restoring Insulin Secretion (RISE) Study. Diabetes Care 2019 Aug;42(8):1521-1529. dc190538; DOI: 10.2337/dc19-0538. PMID: 31177181. 

PMCID: PMC6647043.  PubMed * Journal 


Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Utzschneider, KM, Nadeau KJ, Hannon TS, Sam S, Barengolts, E, Manchanda S, Ehrmann DA, Van Cauter E, The RISE Consortium. Association of Self-Reported Sleep and Circadian Measures With Glycemia in Adults With Prediabetes or Recently Diagnosed Untreated Type 2 Diabetes. Diabetes Care 2019;42(7):1326-1332. dc19-0298. PMID: 31048411. PMCID: PMC6609965. PubMed Journal 

2018/10/03   Xiang AH, Trigo E, Martinez M, Katkhouda N, Beale E, Wang X, Wu J, Chow T, Montgomery C, Nayak K, Hendee F, Buchanan T, RISE Consortium. Impact of Gastric Banding Versus Metformin on β-Cell Function in Adults With Impaired Glucose Tolerance or Mild Type 2 Diabetes. Diabetes Care 2018 Dec;41(12):2544-2551; dc181662 (Epub ahead of print). PMID: 30282699. PMCID: PMC6245202.  PubMed * Journal 

RISE Consortium. Impact of Insulin and Metformin versus Metformin along on Beta Cell Function in Youth with Impaired Glucose Tolerance or Recently Diagnosed Type 2 DIabetes. Diabetes Care 2018 Aug;41(8):1717-1725. doi: 10.2337/dc180787. PMID: 29941500. PMCID: PMC6054504.  PubMed * Journal 


RISE Consortium. Metabolic Contrasts between Youth and Adults with Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: II. Observations Using the Oral Glucose Tolerance Test. Diabetes Care 2018 Aug;41(8):1707-1716. doi: 10.2337/dc180243. PMID: 29941498. PMCID: PMC6054494.  PubMed Journal 


RISE Consortium. Metabolic Contrasts between Youth and Adults with Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: I. Observations Using the Hyperglycemic Clamp. Diabetes Care 2018 Aug;41(8):1696-1706. doi: 10.2337/dc180244. PMID: 29941497 PMCID: PMC6054493. PubMed Journal 


Hannon TS , Kahn SE , Utzschneider KM , Buchanan TA , Nadeau KJ , Zeitler PS , Ehrmann DA , Arslanian SA , Caprio S , Edelstein SL , Savage PJ , Mather KJ ; for the RISE Consortium. Review of methods for measuring β-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium. Diabetes Obes Metab. 2018;20:14–24. PMID: 28493515. PMCID: PMC6095472.  PubMed * Journal 


RISE Consortium. Restoring Insulin Secretion (RISE): design of studies of β-cell preservation in prediabetes and early type 2 diabetes across the life span. Diabetes Care. 2014;37(3):780-8. PMID: 2419450. PMCID: PMC3831376.  doi: 10.2337/dc13-1879.  PubMed * Journal